Tomohide Tatsumi Selected Research

Ribavirin (Virazole)

8/2019	Predictive factors of anemia during sofosbuvir and ribavirin therapy for genotype 2 chronic hepatitis C patients.
1/2019	Efficacy and safety of sofosbuvir-velpatasvir with or without ribavirin in HCV-infected Japanese patients with decompensated cirrhosis: an open-label phase 3 trial.
12/2017	Frequency of, and factors associated with, hepatitis B virus reactivation in hepatitis C patients treated with all-oral direct-acting antivirals: Analysis of a Japanese prospective cohort.
10/2016	Impact of ribavirin dosage in chronic hepatitis C patients treated with simeprevir, pegylated interferon plus ribavirin combination therapy.
3/2016	The impact of an inosine triphosphate pyrophosphatase genotype on bilirubin increase in chronic hepatitis C patients treated with simeprevir, pegylated interferon plus ribavirin.
7/2015	Efficacy of pegylated interferon and ribavirin combination therapy for patients with hepatitis C virus infection after curative resection or ablation for hepatocellular carcinoma--A retrospective multicenter study.
3/2015	The prospective randomized study on telaprevir at 1500 or 2250 mg with pegylated interferon plus ribavirin in Japanese patients with HCV genotype 1.
7/2014	Post-treatment levels of α-fetoprotein predict incidence of hepatocellular carcinoma after interferon therapy.
2/2014	Significance of liver stiffness measurement by acoustic radiation force impulse (ARFI) among hepatitis C patients.
4/2013	Incidence of hepatocellular carcinoma in HCV-infected patients with normal alanine aminotransferase levels categorized by Japanese treatment guidelines.

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Tomohide Tatsumi Research Topics

Disease

55	Neoplasms (Cancer) 01/2024 - 09/2002
55	Hepatocellular Carcinoma (Hepatoma) 01/2024 - 04/2003
26	Chronic Hepatitis C 01/2023 - 02/2003
26	Infections 01/2023 - 02/2003
16	Fibrosis (Cirrhosis) 12/2023 - 03/2011
16	Liver Cirrhosis (Hepatic Cirrhosis) 10/2022 - 10/2004
8	Inflammation (Inflammations) 10/2023 - 02/2010
7	Virus Diseases (Viral Diseases) 01/2022 - 02/2003
6	Chronic Hepatitis (Chronic Active Hepatitis) 01/2022 - 10/2008
6	Liver Diseases (Liver Disease) 01/2022 - 08/2008
6	Liver Neoplasms (Liver Cancer) 09/2016 - 01/2007
5	Pancreatic Neoplasms (Pancreatic Cancer) 10/2023 - 12/2013
5	Hepatitis 01/2021 - 01/2007
5	Hepatitis C 10/2020 - 03/2011
5	Colonic Neoplasms (Colon Cancer) 09/2013 - 01/2003
4	Carcinogenesis 01/2022 - 05/2012
4	Non-alcoholic Fatty Liver Disease 11/2021 - 01/2016
4	Renal Cell Carcinoma (Grawitz Tumor) 01/2021 - 09/2002
4	Chronic Hepatitis B 01/2016 - 02/2006
4	Melanoma (Melanoma, Malignant) 05/2010 - 09/2002
3	Disease Progression 02/2022 - 12/2008
3	Fatty Liver 01/2021 - 07/2017
3	Anemia 08/2019 - 02/2010
3	Hepatitis B 10/2018 - 01/2009
3	Neoplasm Metastasis (Metastasis) 09/2016 - 03/2007
2	Cholangitis 04/2023 - 05/2021
2	Breast Neoplasms (Breast Cancer) 01/2022 - 04/2013
2	Adenocarcinoma 01/2020 - 07/2017
2	Massive Hepatic Necrosis 10/2018 - 01/2007
2	Pancreatitis 01/2018 - 12/2012

Drug/Important Bio-Agent (IBA)

22	Antiviral Agents (Antivirals)IBA 12/2023 - 01/2007
19	Proteins (Proteins, Gene)FDA Link 12/2022 - 03/2003
17	InterferonsIBA 10/2020 - 09/2010
17	Ribavirin (Virazole)FDA LinkGeneric 08/2019 - 01/2011
14	Peptides (Polypeptides)IBA 02/2011 - 09/2002
10	micaIBA 10/2019 - 02/2003
9	Fetal Proteins (Fetoprotein)IBA 01/2024 - 07/2014
9	CytokinesIBA 10/2023 - 10/2002
9	RNA (Ribonucleic Acid)IBA 10/2023 - 03/2012
9	VaccinesIBA 10/2018 - 12/2002
8	SofosbuvirIBA 04/2023 - 11/2015
8	Sorafenib (BAY 43-9006)FDA Link 04/2021 - 04/2010
8	AntigensIBA 05/2010 - 09/2002
7	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2016
6	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 02/2006
6	Small Interfering RNA (siRNA)IBA 07/2017 - 10/2010
6	MHC class I-related chain AIBA 06/2010 - 02/2003
6	EpitopesIBA 12/2008 - 09/2002
5	atezolizumabIBA 01/2024 - 02/2022
5	Bevacizumab (Avastin)FDA Link 01/2024 - 02/2022
5	Glycoproteins (Glycoprotein)IBA 01/2023 - 03/2011
5	Lamivudine (Epivir)FDA Link 05/2012 - 06/2008
5	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2007 - 08/2003
4	lenvatinibIBA 07/2022 - 11/2019
4	Aspartate Aminotransferases (Aspartate Transaminase)IBA 11/2021 - 02/2014
4	BilirubinIBA 09/2020 - 10/2009
4	Transcription Factors (Transcription Factor)IBA 01/2020 - 12/2012
4	NucleotidesIBA 11/2015 - 01/2007
4	alpha-galactosylceramideIBA 06/2009 - 08/2003
4	LigandsIBA 12/2008 - 11/2003
3	velpatasvirIBA 04/2023 - 01/2019
3	Connective Tissue Growth FactorIBA 01/2023 - 08/2011
3	InterleukinsIBA 01/2023 - 10/2002
3	Interleukin-6 (Interleukin 6)IBA 01/2023 - 11/2007
3	Phosphotransferases (Kinase)IBA 01/2023 - 10/2010
3	Messenger RNA (mRNA)IBA 12/2022 - 05/2010
3	Growth Differentiation Factor 15IBA 01/2022 - 01/2021
3	Hepatitis B e AntigensIBA 01/2022 - 05/2012
3	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2022 - 04/2013
3	ledipasvirIBA 01/2021 - 11/2015
3	Acetylcysteine (Siran)FDA LinkGeneric 01/2021 - 08/2015
3	sofosbuvir drug combination ledipasvirIBA 08/2018 - 12/2017
3	SimeprevirIBA 07/2017 - 03/2016
3	MicroRNAs (MicroRNA)IBA 05/2017 - 05/2010
3	entecavir FDA Link 07/2015 - 06/2008
3	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2008 - 01/2003
3	EphA2 ReceptorIBA 12/2008 - 08/2005
3	Transforming Growth Factor beta (TGF-beta)IBA 11/2008 - 10/2004
2	AlbuminsIBA 01/2022 - 09/2020
2	HaptoglobinsIBA 01/2022 - 01/2016
2	Hyaluronic Acid (Hyaluronan)IBA 01/2022 - 11/2021
2	LipidsIBA 01/2022 - 12/2016
2	Warfarin (Coumadin)FDA LinkGeneric 01/2022 - 11/2019
2	pgRNAIBA 01/2022 - 01/2020
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 01/2022 - 07/2015
2	EnzymesIBA 05/2021 - 08/2003
2	Nonesterified Fatty Acids (NEFA)IBA 01/2021 - 07/2017
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2020 - 11/2007
2	Lipase (Acid Lipase)FDA Link 01/2018 - 12/2012
2	telaprevirIBA 07/2017 - 03/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2016 - 08/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2016 - 12/2012
2	Branched-Chain Amino AcidsIBA 09/2016 - 07/2013
2	Inosine Triphosphate (ITP)IBA 03/2016 - 03/2014
2	CholesterolIBA 01/2016 - 11/2014

Therapy/Procedure

37	Therapeutics 01/2024 - 12/2002
7	Immunotherapy 01/2023 - 12/2002
6	Drug Therapy (Chemotherapy) 12/2022 - 10/2009
2	Radiofrequency Ablation 12/2022 - 07/2015
2	Radiotherapy 01/2022 - 12/2013